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Amniocentesis Test: Everything You Need to Know

11 Sep, 2023

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Pregnancy is a time of joy and anticipation, but it can also be marked by important decisions and choices. One such decision that expectant parents might encounter is whether or not to undergo an amniocentesis test. In this Blog post, we'll delve into the world of amniocentesis, exploring what it is, when it's recommended, the procedure itself, and the critical considerations that come with it.

1.Understanding Amniocentesis

Amniocentesis is a medical procedure that provides valuable insights into the health and development of a fetus during pregnancy. It involves the extraction of a small amount of amniotic fluid from the amniotic sac surrounding the fetus. This fluid contains fetal cells that can be analyzed to detect various genetic, chromosomal, and developmental abnormalities.

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2.When Is Amniocentesis Recommended?

This diagnostic test is typically recommended when there is an increased risk of genetic or chromosomal abnormalities in the developing fetus. Common reasons include:

  1. Advanced Maternal Age: Women aged 35 and older are at a higher risk of having a baby with chromosomal abnormalities like Down syndrome.
  2. Previous Pregnancy Complications: If a woman has had a previous pregnancy with a chromosomal abnormality, she may be advised to undergo amniocentesis in subsequent pregnancies.
  3. Abnormal Prenatal Screening Results: Abnormal results from other prenatal tests may prompt further evaluation through amniocentesis.
  4. Family History: A family history of genetic disorders or a known genetic condition in one or both parents can warrant amniocentesis.
  5. Concerns Raised During Ultrasound: If an ultrasound examination reveals potential developmental or structural abnormalities, amniocentesis may be suggested.

3.The Amniocentesis Procedure

Amniocentesis is usually performed between the 15th and 20th week of pregnancy, although it can be done later if necessary. The procedure involves several steps:

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  1. Preparation: The woman's abdomen is cleaned and sterilized.
  2. Ultrasound Guidance: An ultrasound is used to locate the fetus and the safest area to insert the needle.
  3. Needle Insertion: A thin, hollow needle is carefully inserted through the abdominal wall and into the amniotic sac.
  4. Amniotic Fluid Extraction: A small amount of amniotic fluid (usually about 20 ml) is withdrawn and collected for analysis.
  5. Monitoring: The baby's heart rate is monitored throughout the procedure to ensure their well-being.
  6. Aftercare: After the procedure, the woman may need to rest for a short time, and her healthcare provider will monitor her for any signs of complications.

4.Benefits and Risks of Amniocentesis

Like any medical procedure, amniocentesis has its advantages and potential risks:

4.1. Benefits:

  • Accurate diagnosis of genetic or chromosomal conditions.
  • Informed decision-making regarding pregnancy management.
  • Early preparation for the needs of a child with special medical requirements.

4.2. Risks:

  • Risk of miscarriage (approximately 1 in 300 to 1 in 500 procedures).
  • Potential for infection or injury to the fetus or mother, although these risks are rare when the procedure is performed by an experienced healthcare provider.
  • Emotional stress and anxiety related to waiting for results and potential outcomes.

5. After Amniocentesis: What Comes Next?

After the amniocentesis procedure, the collected amniotic fluid is sent to a laboratory for analysis, which typically takes a few days to a couple of weeks. Once the results are available, they are discussed with the expectant parents, and decisions regarding pregnancy management are made based on the findings.
Expectant parents should be prepared for a range of possible outcomes and work closely with their healthcare provider to make informed choices that align with their values and circumstances.

6.Top 5 Indian Hospitals for Amniocentesis Testing

6.1. Apollo Hospitals, Chennai

  • Pioneers in Prenatal Care
  • Renowned for its advanced maternity and fetal medicine services, including amniocentesis.
  • Specialists: Dr. Vasantha Lakshmi, Dr. Meena Muthiah, and Dr. S. Vijaya Kumar in fetal medicine.

6.2. AIIMS (All India Institute of Medical Sciences), Delhi

  • Leaders in Medical Excellence
  • One of India's premier medical institutions, AIIMS offers comprehensive prenatal diagnostics, including amniocentesis.
  • Specialists: Prof. M.C. Misra and Dr. Vandana Bansal in the Department of Obstetrics & Gynecology.

6.3. Medanta - The Medicity, Gurgaon

  • Advanced Maternal-Fetal Care
  • Known for its advanced maternal-fetal medicine services and a dedicated prenatal diagnostic unit.
  • Specialists: Dr. Shobha Sharma and Dr. Richa Saxena in fetal medicine.

6.4. Kokilaben Dhirubhai Ambani Hospital, Mumbai

  • Pioneers in Prenatal Diagnostics
  • Offers a wide range of prenatal diagnostic services, including amniocentesis.
  • Specialists: Dr. Nozer Sheriar and Dr. Duru Shah in maternal-fetal medicine.

6.5. Manipal Hospitals, Bangalore

  • Comprehensive Prenatal Services
  • Known for its advanced obstetrics and gynecology services, including prenatal testing.
  • Specialists: Dr. Sunita Seshadri and Dr. Manju Nair in fetal medicine.

These hospitals are renowned for their expertise in prenatal diagnostics, including amniocentesis, and have experienced specialists who provide comprehensive care to expectant parents.


Amniocentesis is a valuable tool in prenatal care, offering essential information about a developing fetus's health. While it's not a decision to be taken lightly, the knowledge gained through amniocentesis can provide peace of mind and guide choices throughout the remainder of the pregnancy journey. It's essential for expectant parents to have open and informed discussions with their healthcare provider to determine if amniocentesis is the right choice for them and their baby.

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Amniocentesis is a medical procedure during which a small amount of amniotic fluid is collected from the amniotic sac surrounding a developing fetus. The fluid is then analyzed for various genetic, chromosomal, and developmental abnormalities.